An early urn is available in a cemetery outside Rome. Once opened, it activates a number of violent episodes: while several cryptic young women coming from throughout the globe are accumulating in the town, murders, rapes and robberies rise dramatically. All these incidents are brought on by the return of Mater Lacrimarum, the past of three witches that were spreading death and terror for countless decades. Alone against a military of allies and psychos, Sarah Mandy, an art student who seems to have supernatural abilities of its , is from destroying Rome, the only man left to protect against the Mother of Tears.